If There Are No Side Effects, This Must Be Honduras

Culled from The Physician's Desk Reference -- the standard sourcebook for U.S. doctors, containing information drug companies supply about their products -- and comparable foreign guidebooks.

Chart excerpted by Carolyn Marshall


Tetracycline

[ANTIBIOTIC USED AGAINST VARIOUS INFECTIONS; LEDERLE LABORATORIES.]

Ovulen

[BIRTH CONTROL PILLS; G.D. SEARLE CO.]

Imipramine

[ANTI-DEPRESSANT; CIBA-GEIGY.]

UNITED STATES Caution against use:

By infants, children; during pregnancy; with liver or kidney impairment (latter can be fatal) or if overly sensitive to light.

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Adverse reactions publicized:

Vomiting, diarrhea, nausea, upset stomach, rashes, kidney poisoning. Can poison fetus. Caution against use:

If patient has tendency to blood clot, liver dysfunction, abnormal vaginal bleeding, epilepsy, migraine, asthma, heart trouble.

Adverse reactions publicized:

Nausea, loss of hair, nervousness, jaundice, high blood pressure, weight change, headaches. Caution against use:

If patient has heart disease, history of urinary retention, history of seizures, manic disorder or is on typhoid medication. Not recommended for children or during pregnancy.

Adverse reactions publicized:

Hypertension, stroke, stumbling, delusions, insomnia, numbness, dry mouth, blurred vision, constipation, itching, nausea, vomiting, loss of appetite, diarrhea, sweating. Tetracycline Ovulen Imipramine MEXICO Caution against use:

By infants, children; during pregnancy or if overly sensitive to light.

Adverse reactions publicized

Vomiting, diarrhea, nausea, upset stomach. Caution against use:

If patient has tendency to blood clot, liver dysfunction.

Adverse reactions publicized

Nausea, weight change. Caution against use:

During first trimester of pregnancy.

Adverse reactions publicized

Dry mouth, constipation, itching, sweating. Tetracycline Ovulen Imipramine CENTRAL AMERICA Caution against use:

None.

Adverse reactions publicized

None Caution against use:

If patient has tendency to blood clot, liver dysfunction.

Adverse reactions publicized

Nausea, weight change. Caution against use:

If patient has heart disease.

Adverse reactions publicized

None Tetracycline Ovulen Imipramine BRAZIL Caution against use:

By infants, children; during pregnancy.

Adverse reactions publicized

Vomiting, nausea, upset stomach, rashes. Caution against use:

If patient has tendency to blood clot.

Adverse reactions publicized

None Caution against use:

If patient has heart disease. Not recommended for children or during pregnancy.

Adverse reactions publicized

None Tetracycline Ovulen Imipramine ARGENTINA Caution against use:

None

Adverse reactions publicized

None Caution against use:

If patient has tendency to blood clot.

Adverse reactions publicized

None Caution against use:

May exaggerate response to alcohol.

Adverse reactions publicized

None

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