What’s So Great About STAR*D?

Fight disinformation: Sign up for the free Mother Jones Daily newsletter and follow the news that matters.


Treatment for depression costs the United States a staggering $83 billion each year. Part of this is due to the fact that the treatments themselves involve so much trial and error; there’s very little reliable information out on the effectiveness of various drugs and forms of therapy.

So it’s good news that today Slate is reporting on a new study called STAR*D, conducted by the National Institute of Mental Health, that compares and contrasts the twenty options for prescription antidepressants, their dosages, and even the effects of psychotherapy — something no other study has ever done. For the 19 million Americans who suffer from depression, this is a major step forward. The pharmaceutical industry usually doesn’t produce any comparative data on depression, a state of affairs that has previously left most patients and their doctors guessing which treatment will be the best fit.

Comparative, independent trials will also enable doctors to rely less on collected by the pharmaceutical industry. Mark Gibson, deputy director of the Center for Evidence-Based Policy at Oregon Health and Science University, adds that in regards to data provided by drug firms, “it’s not unusual for less than 10 percent of studies to meet our standards of quality.” And according to Jerry Avorn, professor of medicine at Harvard, comparative studies could motivate drug companies to develop more advanced versions of current drugs, improving on what we already have.

WE'LL BE BLUNT:

We need to start raising significantly more in donations from our online community of readers, especially from those who read Mother Jones regularly but have never decided to pitch in because you figured others always will. We also need long-time and new donors, everyone, to keep showing up for us.

In "It's Not a Crisis. This Is the New Normal," we explain, as matter-of-factly as we can, what exactly our finances look like, how brutal it is to sustain quality journalism right now, what makes Mother Jones different than most of the news out there, and why support from readers is the only thing that keeps us going. Despite the challenges, we're optimistic we can increase the share of online readers who decide to donate—starting with hitting an ambitious $300,000 goal in just three weeks to make sure we can finish our fiscal year break-even in the coming months.

Please learn more about how Mother Jones works and our 47-year history of doing nonprofit journalism that you don't find elsewhere—and help us do it with a donation if you can. We've already cut expenses and hitting our online goal is critical right now.

payment methods

WE'LL BE BLUNT

We need to start raising significantly more in donations from our online community of readers, especially from those who read Mother Jones regularly but have never decided to pitch in because you figured others always will. We also need long-time and new donors, everyone, to keep showing up for us.

In "It's Not a Crisis. This Is the New Normal," we explain, as matter-of-factly as we can, what exactly our finances look like, how brutal it is to sustain quality journalism right now, what makes Mother Jones different than most of the news out there, and why support from readers is the only thing that keeps us going. Despite the challenges, we're optimistic we can increase the share of online readers who decide to donate—starting with hitting an ambitious $300,000 goal in just three weeks to make sure we can finish our fiscal year break-even in the coming months.

Please learn more about how Mother Jones works and our 47-year history of doing nonprofit journalism that you don't find elsewhere—and help us do it with a donation if you can. We've already cut expenses and hitting our online goal is critical right now.

payment methods

We Recommend

Latest

Sign up for our free newsletter

Subscribe to the Mother Jones Daily to have our top stories delivered directly to your inbox.

Get our award-winning magazine

Save big on a full year of investigations, ideas, and insights.

Subscribe

Support our journalism

Help Mother Jones' reporters dig deep with a tax-deductible donation.

Donate