Ohio Gov. John Kasich will drop out of the Republican presidential race on Wednesday afternoon, according to Politico and the Associated Press, effectively handing the nomination to businessman Donald Trump. Kasich’s decision came on the heels of Trump’s blowout victory in the Indiana primary. Texas Sen. Ted Cruz, who’s the party’s second-leading vote-getter, dropped out after the race was called Tuesday night. Kasich canceled a media event this morning in Washington, DC, and has scheduled a news conference for 5 p.m. in Columbus, Ohio.