My Memory is a Hazy Fog. How About Yours?


I desperately need a shot of PKMzeta, an enzyme that mediates long-term memory:

What does PKMzeta do? The molecule’s crucial trick is that it increases the density of a particular type of sensor called an AMPA receptor on the outside of a neuron….This process requires constant upkeep—every long-term memory is always on the verge of vanishing. As a result, even a brief interruption of PKMzeta activity can dismantle the function of a steadfast circuit.

If the genetic expression of PKMzeta is amped up—by, say, genetically engineering rats to overproduce the stuff—they become mnemonic freaks, able to convert even the most mundane events into long-term memory. (Their performance on a standard test of recall is nearly double that of normal animals.)

My memory has always been terrible. My mother is nearly 80 and still remembers classmates from her kindergarten days. I barely even remember going to kindergarten. Actually, that’s too charitable: I don’t remember going to kindergarten. Or first grade. Or fifth grade. Or high school. Or college. Or, for that matter, stuff I did two years ago.

Is this an exaggeration? Only barely. I remember occasional shreds from years past, but that’s about it. On the bright side, this means that if I had a nasty fight with you a few years ago, there’s a good chance I have no memory of it. On the not-so-bright side, it means that if we were close friends in high school, I might or might not even remember knowing you, let alone remember anything substantive about what we did together.

So which are you? Is the past just a hazy fog, as it is for me? Or do you have sharp memories going all the way back to your third birthday? Or something in between?

DOES IT FEEL LIKE POLITICS IS AT A BREAKING POINT?

Headshot of Editor in Chief of Mother Jones, Clara Jeffery

It sure feels that way to me, and here at Mother Jones, we’ve been thinking a lot about what journalism needs to do differently, and how we can have the biggest impact.

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We aim to hire, build a team, and give them the time and space needed to understand how we got here and how we might get out. We want to dig into the forces and decisions that have allowed massive conflicts of interest, influence peddling, and win-at-all-costs politics to flourish.

It's unlike anything we've done, and we have seed funding to get started, but we're looking to raise $500,000 from readers by July when we'll be making key budgeting decisions—and the more resources we have by then, the deeper we can dig. If our plan sounds good to you, please help kickstart it with a tax-deductible donation today.

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Signed by Clara Jeffery

Clara Jeffery, Editor-in-Chief

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