Quiet Your Legs, Gamble Your Lifesavings, New Drugs Do All This and More

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A study from the Mayo Clinic says that a class of drugs used to treat restless leg syndrome has the bizarre side effect of turning regular folks into compulsive gamblers. (… note to Karl Rove: GWB’s excuse?…) The modern world is strange, but no stranger than this: peddling a new drug for a syndrome no one’s ever heard of and then creating a solution far worse than the problem.

Compulsive gambling with extreme losses — in two cases, greater than $100,000 — by people without a prior history of gambling problems has been linked to a class of drugs commonly used to treat the neurological disorder restless legs syndrome (RLS). A new Mayo Clinic study is the first to describe this compulsive gambling in RLS patients who are being treated with medications that stimulate dopamine receptors in the brain.

One patient, a woman seen in the Mayo Clinic Sleep Disorders Center, had a five-year history of regular nighttime creeping-crawling sensations in her legs, accompanied by the strong urge to move her legs. Two and a half years prior to her Mayo Clinic visit, she had been diagnosed with RLS and treatment with pramipexole was begun.

Her symptoms improved, however, a problematic behavior developed soon after she started taking the medication. She developed an uncontrollable urge to gamble when visiting the nearby casino. As the dose increased, her gambling compulsion grew stronger. The transition of her therapy to another dopamine agonist, ropinirole, further increased her compulsion to gamble. Prior to her treatment for RLS, she had no history of gambling and viewed gamblers as “unfortunate individuals,” the authors report. The patient lost more than $140,000 from gambling.

THE BIG PICTURE

You expect the big picture, and it's our job at Mother Jones to give it to you. And right now, so many of the troubles we face are the making not of a virus, but of the quest for profit, political or economic (and not just from the man in the White House who could have offered leadership and comfort but instead gave us bleach).

In "News Is Just Like Waste Management," we unpack what the coronavirus crisis has meant for journalism, including Mother Jones’, and how we can rise to the challenge. If you're able to, this is a critical moment to support our nonprofit journalism with a donation: We've scoured our budget and made the cuts we can without impairing our mission, and we hope to raise $400,000 from our community of online readers to help keep our big reporting projects going because this extraordinary pandemic-plus-election year is no time to pull back.

THE BIG PICTURE

You expect the big picture, and it's our job at Mother Jones to give it to you. And right now, so many of the troubles we face are the making not of a virus, but of the quest for profit, political or economic (and not just from the man in the White House who could have offered leadership and comfort but instead gave us bleach).

In "News Is Just Like Waste Management," we unpack what the coronavirus crisis has meant for journalism, including Mother Jones’, and how we can rise to the challenge. If you're able to, this is a critical moment to support our nonprofit journalism with a donation: We've scoured our budget and made the cuts we can without impairing our mission, and we hope to raise $400,000 from our community of online readers to help keep our big reporting projects going because this extraordinary pandemic-plus-election year is no time to pull back.

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