Culled from The Physician’s Desk Reference — the standard sourcebook for U.S. doctors, containing information drug companies supply about their products — and comparable foreign guidebooks.
Chart excerpted by Carolyn Marshall
| Tetracycline
[ANTIBIOTIC USED AGAINST VARIOUS INFECTIONS; LEDERLE LABORATORIES.] |
Ovulen
[BIRTH CONTROL PILLS; G.D. SEARLE CO.] |
Imipramine
[ANTI-DEPRESSANT; CIBA-GEIGY.] |
|
| UNITED STATES | Caution against use:
By infants, children; during pregnancy; with liver or kidney impairment (latter can be fatal) or if overly sensitive to light. Adverse reactions publicized: Vomiting, diarrhea, nausea, upset stomach, rashes, kidney poisoning. Can poison fetus. |
Caution against use:
If patient has tendency to blood clot, liver dysfunction, abnormal vaginal bleeding, epilepsy, migraine, asthma, heart trouble. Adverse reactions publicized: Nausea, loss of hair, nervousness, jaundice, high blood pressure, weight change, headaches. |
Caution against use:
If patient has heart disease, history of urinary retention, history of seizures, manic disorder or is on typhoid medication. Not recommended for children or during pregnancy. Adverse reactions publicized: Hypertension, stroke, stumbling, delusions, insomnia, numbness, dry mouth, blurred vision, constipation, itching, nausea, vomiting, loss of appetite, diarrhea, sweating. |
| Tetracycline | Ovulen | Imipramine | |
| MEXICO | Caution against use:
By infants, children; during pregnancy or if overly sensitive to light. Adverse reactions publicized Vomiting, diarrhea, nausea, upset stomach. |
Caution against use:
If patient has tendency to blood clot, liver dysfunction. Adverse reactions publicized Nausea, weight change. |
Caution against use:
During first trimester of pregnancy. Adverse reactions publicized Dry mouth, constipation, itching, sweating. |
| Tetracycline | Ovulen | Imipramine | |
| CENTRAL AMERICA | Caution against use:
None. Adverse reactions publicized None |
Caution against use:
If patient has tendency to blood clot, liver dysfunction. Adverse reactions publicized Nausea, weight change. |
Caution against use:
If patient has heart disease. Adverse reactions publicized None |
| Tetracycline | Ovulen | Imipramine | |
| BRAZIL | Caution against use:
By infants, children; during pregnancy. Adverse reactions publicized Vomiting, nausea, upset stomach, rashes. |
Caution against use:
If patient has tendency to blood clot. Adverse reactions publicized None |
Caution against use:
If patient has heart disease. Not recommended for children or during pregnancy. Adverse reactions publicized None |
| Tetracycline | Ovulen | Imipramine | |
| ARGENTINA | Caution against use:
None Adverse reactions publicized None |
Caution against use:
If patient has tendency to blood clot. Adverse reactions publicized None |
Caution against use:
May exaggerate response to alcohol. Adverse reactions publicized None |
